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Cinnamophilin overcomes cancer multi-drug resistance via allosterically modulating human P-glycoprotein on both drug binding sites and ATPase binding sites.
Teng, Yu-Ning; Huang, Bo-Hau; Huang, Shih-Ya; Wu, I-Ting; Wu, Tian-Shung; Lee, Tsui-Er; Hung, Chin-Chuan.
Affiliation
  • Teng YN; School of Medicine, College of Medicine, I-Shou University, 8 Yida Road, Kaohsiung 82445, Taiwan, ROC. Electronic address: eunicegh520@gmail.com.
  • Huang BH; Department of Pharmacy, China Medical University Hsinchu Hospital, No. 199, Section1, Xinglong Rd., Zhubei City, Hsinchu Country 302056, Taiwan, ROC. Electronic address: huangbohau@gmail.com.
  • Huang SY; Department of Pharmacy, College of Pharmacy, China Medical University, 100, Section 1, Jingmao Rd., Beitun Dist., Taichung City 406040, Taiwan, ROC. Electronic address: u103003714@cmu.edu.tw.
  • Wu IT; Department of Pharmacy, College of Pharmacy, China Medical University, 100, Section 1, Jingmao Rd., Beitun Dist., Taichung City 406040, Taiwan, ROC. Electronic address: u105015202@cmu.edu.tw.
  • Wu TS; School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan, ROC; Department of Pharmacy, College of Pharmacy and Health Care, Tajen University, Pingtung 907, Taiwan, ROC. Electronic address: tswu@ncku.edu.tw.
  • Lee TE; Office of Physical Education, Asia University, 500, Lioufeng Rd., Wufeng, Taichung 41354, Taiwan, ROC. Electronic address: vivian@asia.edu.tw.
  • Hung CC; Department of Pharmacy, College of Pharmacy, China Medical University, 100, Section 1, Jingmao Rd., Beitun Dist., Taichung City 406040, Taiwan, ROC; Department of Pharmacy, China Medical University Hospital, 2 Yude Road, Taichung 40447, Taiwan, ROC; Department of Healthcare Administration, Asia Univ
Biomed Pharmacother ; 144: 112379, 2021 Dec.
Article in En | MEDLINE | ID: mdl-34794239
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenosine Triphosphatases / Lignans / ATP Binding Cassette Transporter, Subfamily B, Member 1 / Drug Resistance, Neoplasm / Enzyme Inhibitors / Guaiacol Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2021 Document type: Article Country of publication: Francia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenosine Triphosphatases / Lignans / ATP Binding Cassette Transporter, Subfamily B, Member 1 / Drug Resistance, Neoplasm / Enzyme Inhibitors / Guaiacol Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2021 Document type: Article Country of publication: Francia