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A facile design of thio-perylenediimides with controllable fluorescent, photodynamic and photothermal effects towards cancer theranostics.
Liu, Chang; Ji, Chendong; Fan, Zongyang; Ma, Ruihao; Yin, Meizhen.
Affiliation
  • Liu C; State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, China. yinmz@mail.buct.edu.cn.
  • Ji C; State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, China. yinmz@mail.buct.edu.cn.
  • Fan Z; State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, China. yinmz@mail.buct.edu.cn.
  • Ma R; State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, China. yinmz@mail.buct.edu.cn.
  • Yin M; State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, China. yinmz@mail.buct.edu.cn.
Chem Commun (Camb) ; 57(97): 13126-13129, 2021 Dec 07.
Article in En | MEDLINE | ID: mdl-34807201
ABSTRACT
A series of thionated perylenediimides with modulating phototheranostic modalities have been synthesized by a one-pot method for multiple anti-cancer applications. Compared to the initial and 4-tert-butyl phenol-substituted fluorescent perylenediimide, the obtained monothionated perylenediimide became photodynamic. With the increase of thionation degree, tetrathionated perylenediimide changed into an optimal photothermal agent.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Perylene / Photochemotherapy / Sulfhydryl Compounds / Breast Neoplasms / Photosensitizing Agents / Fluorescence / Imides / Antineoplastic Agents Limits: Animals Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: China Publication country: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Perylene / Photochemotherapy / Sulfhydryl Compounds / Breast Neoplasms / Photosensitizing Agents / Fluorescence / Imides / Antineoplastic Agents Limits: Animals Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: China Publication country: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM