Candida keratitis and endopthalmitis after corneal transplantation; two case reports, a novel regimen and literature overview of therapeutic options.
Eur J Ophthalmol
; : 11206721211060140, 2021 Nov 23.
Article
in En
| MEDLINE
| ID: mdl-34812090
ABSTRACT
PURPOSE:
To evaluate treatment options for candida keratitis and endopthalmitis after corneal transplantation.METHODS:
Case reports and literature review.RESULTS:
Two patients with keratitis due to Candida glabrata/parapsilosis after corneal transplantation were successfully treated with a combination of topical voriconazole, intracameral voriconazole and amphotericin B, and systemic treatment with flucytosine.CONCLUSIONS:
Natamycine and voriconazole topically are preferred therapeutic options for the treatment of fungal keratitis. Systemic flucytosine is a useful alternative additive, particularly for countries where natamycine is not registered as a pharmaceutical agent.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Eur J Ophthalmol
Journal subject:
OFTALMOLOGIA
Year:
2021
Document type:
Article
Affiliation country:
Países Bajos