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A new mouse model of Ehlers-Danlos syndrome generated using CRISPR/Cas9-mediated genomic editing.
Nitahara-Kasahara, Yuko; Mizumoto, Shuji; Inoue, Yukiko U; Saka, Shota; Posadas-Herrera, Guillermo; Nakamura-Takahashi, Aki; Takahashi, Yuki; Hashimoto, Ayana; Konishi, Kohei; Miyata, Shinji; Masuda, Chiaki; Matsumoto, Emi; Maruoka, Yasunobu; Yoshizawa, Takahiro; Tanase, Toshiki; Inoue, Takayoshi; Yamada, Shuhei; Nomura, Yoshihiro; Takeda, Shin'ichi; Watanabe, Atsushi; Kosho, Tomoki; Okada, Takashi.
Affiliation
  • Nitahara-Kasahara Y; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo 113-8603, Japan.
  • Mizumoto S; Division of Molecular and Medical Genetics, Center for Gene and Cell Therapy, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Inoue YU; Department of Pathobiochemistry, Faculty of Pharmacy, Meijo University, Nagoya 468-8503, Japan.
  • Saka S; Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira 187-8502, Japan.
  • Posadas-Herrera G; Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu 183-8509, Japan.
  • Nakamura-Takahashi A; Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira 187-8502, Japan.
  • Takahashi Y; Division of Molecular and Medical Genetics, Center for Gene and Cell Therapy, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
  • Hashimoto A; Department of Pharmacology, Tokyo Dental College, Tokyo 101-0061, Japan.
  • Konishi K; Department of Medical Genetics, Shinshu University School of Medicine, Matsumoto 390-8621, Japan.
  • Miyata S; Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu 183-8509, Japan.
  • Masuda C; Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu 183-8509, Japan.
  • Matsumoto E; Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu 183-8509, Japan.
  • Maruoka Y; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo 113-8603, Japan.
  • Yoshizawa T; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo 113-8603, Japan.
  • Tanase T; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo 113-8603, Japan.
  • Inoue T; Division of Animal Research, Research Center for Supports to Advanced Science, Shinshu University, Matsumoto 390-8621, Japan.
  • Yamada S; Department of Pediatric Dentistry, Tokyo Dental College, Tokyo 101-0061, Japan.
  • Nomura Y; Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira 187-8502, Japan.
  • Takeda S; Department of Pathobiochemistry, Faculty of Pharmacy, Meijo University, Nagoya 468-8503, Japan.
  • Watanabe A; Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu 183-8509, Japan.
  • Kosho T; Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira 187-8502, Japan.
  • Okada T; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo 113-8603, Japan.
Dis Model Mech ; 14(12)2021 12 01.
Article in En | MEDLINE | ID: mdl-34850861
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ehlers-Danlos Syndrome Limits: Animals / Pregnancy Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2021 Document type: Article Affiliation country: Japón Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ehlers-Danlos Syndrome Limits: Animals / Pregnancy Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2021 Document type: Article Affiliation country: Japón Country of publication: Reino Unido