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Hexarelin attenuates abdominal aortic aneurysm formation by inhibiting SMC phenotype switch and inflammasome activation.
Jiang, Bo; Wang, Mo; Li, Xue; Ren, Pengwei; Li, Guangxin; Wang, Yuqi; Wang, Lei; Li, Xuan; Yang, Dong; Qin, Lingfeng; Xin, Shijie.
Affiliation
  • Jiang B; Department of Vascular Surgery, The First Hospital of China Medical University, Key Laboratory of Pathogenesis, Prevention and Therapeutics of Aortic Aneurysm, Shenyang, Liaoning 110001, China.
  • Wang M; Department of Surgery, Yale School of Medicine, New Haven, CT 06519, USA.
  • Li X; Department of Nephrology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, China.
  • Ren P; Department of Surgery, Yale School of Medicine, New Haven, CT 06519, USA.
  • Li G; Department of Breast and Thyroid Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, China.
  • Wang Y; Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06520, USA; Department of Biomedical Engineering, Yale University, New Haven, CT 06520, USA.
  • Wang L; Department of Vascular Surgery, The First Hospital of China Medical University, Key Laboratory of Pathogenesis, Prevention and Therapeutics of Aortic Aneurysm, Shenyang, Liaoning 110001, China.
  • Li X; Department of Vascular Surgery, The First Hospital of China Medical University, Key Laboratory of Pathogenesis, Prevention and Therapeutics of Aortic Aneurysm, Shenyang, Liaoning 110001, China.
  • Yang D; Department of Vascular Surgery, The First Hospital of China Medical University, Key Laboratory of Pathogenesis, Prevention and Therapeutics of Aortic Aneurysm, Shenyang, Liaoning 110001, China.
  • Qin L; Department of Surgery, Yale School of Medicine, New Haven, CT 06519, USA. Electronic address: lingfeng.qin@yale.edu.
  • Xin S; Department of Vascular Surgery, The First Hospital of China Medical University, Key Laboratory of Pathogenesis, Prevention and Therapeutics of Aortic Aneurysm, Shenyang, Liaoning 110001, China. Electronic address: sjxin@cmu.edu.cn.
Microvasc Res ; 140: 104280, 2022 03.
Article in En | MEDLINE | ID: mdl-34856183
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Aortic Aneurysm, Abdominal / Myocytes, Smooth Muscle / Inflammasomes / Cell Plasticity / NLR Family, Pyrin Domain-Containing 3 Protein / Anti-Inflammatory Agents / Muscle, Smooth, Vascular Type of study: Prognostic_studies Limits: Animals Language: En Journal: Microvasc Res Year: 2022 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Aortic Aneurysm, Abdominal / Myocytes, Smooth Muscle / Inflammasomes / Cell Plasticity / NLR Family, Pyrin Domain-Containing 3 Protein / Anti-Inflammatory Agents / Muscle, Smooth, Vascular Type of study: Prognostic_studies Limits: Animals Language: En Journal: Microvasc Res Year: 2022 Document type: Article Affiliation country: China