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A Biocompatible Vibration-Actuated Omni-Droplets Rectifier with Large Volume Range Fabricated by Femtosecond Laser.
Zhang, Yiyuan; Li, Jing; Xiang, Le; Wang, Jinxing; Wu, Tao; Jiao, Yunlong; Jiang, Shaojun; Li, Chuanzong; Fan, Shengying; Zhang, Juan; Wu, Hao; Zhang, Yuxuan; Bian, Yucheng; Zhao, Kun; Peng, Yubin; Zhu, Wulin; Li, Jiawen; Hu, Yanlei; Wu, Dong; Chu, Jiaru; Wang, Zuankai.
Affiliation
  • Zhang Y; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Li J; Department of Mechanical Engineering, City University of Hong Kong, Hong Kong, China.
  • Xiang L; School of Instrument Science and Opto-electronics Engineering, Hefei University of Technology, Hefei, 230009, P. R. China.
  • Wang J; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Wu T; Department of Modern Mechanics, University of Science and Technology of China, Hefei, 230027, China.
  • Jiao Y; Institute of Tribology, Hefei University of Technology, Hefei, 230009, P. R. China.
  • Jiang S; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Li C; School of Instrument Science and Opto-electronics Engineering, Hefei University of Technology, Hefei, 230009, P. R. China.
  • Fan S; Center for Biomedical Engineering Department of Electronic Science and Technology, University of Science and Technology of China, Hefei, 230026, China.
  • Zhang J; Department of Clinical Laboratory, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China.
  • Wu H; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Zhang Y; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Bian Y; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Zhao K; Information Materials and Intelligent Sensing Laboratory of Anhui Province, School of Electronics and Information Engineering, Anhui University, Hefei, 230039, China.
  • Peng Y; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Zhu W; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Li J; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Hu Y; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Wu D; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Chu J; CAS Key Laboratory of Mechanical Behavior and Design of Materials, Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, 230027, China.
  • Wang Z; Department of Mechanical Engineering, City University of Hong Kong, Hong Kong, China.
Adv Mater ; 34(12): e2108567, 2022 Mar.
Article in En | MEDLINE | ID: mdl-34865264
ABSTRACT
High-performance droplet transport is crucial for diverse applications including biomedical detection, chemical micro-reaction, and droplet microfluidics. Despite extensive progress, traditional passive and active strategies are restricted to limited liquid types, small droplet volume ranges, and poor biocompatibilities. Moreover, more challenges occur for biological fluids due to large viscosity and low surface tension. Here, a vibration-actuated omni-droplets rectifier (VAODR) consisting of slippery ratchet arrays fabricated by femtosecond laser and vibration platforms is reported. Through the relative competition between the asymmetric adhesive resistance originating from the lubricant meniscus on the VAODR and the periodic inertial driving force originating from isotropic vibration, the fast (up to ≈60 mm s-1 ), programmable, and robust transport of droplets is achieved for a large volume range (0.05-2000 µL, Vmax /Vmin  ≈ 40 000) and in various transport modes including transport of liquid slugs in tubes, programmable and sequential transport, and bidirectional transport. This VAODR is general to a high diversity of biological and medical fluids, and thus can be used for biomedical detection including ABO blood-group tests and anticancer drugs screening. These strategies provide a complementary and promising platform for maneuvering omni-droplets that are fundamental to biomedical applications and other high-throughput omni-droplet operation fields.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vibration / Microfluidics Language: En Journal: Adv Mater Journal subject: BIOFISICA / QUIMICA Year: 2022 Document type: Article Affiliation country: China

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vibration / Microfluidics Language: En Journal: Adv Mater Journal subject: BIOFISICA / QUIMICA Year: 2022 Document type: Article Affiliation country: China