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Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging.
Michno, Wojciech; Wehrli, Patrick M; Koutarapu, Srinivas; Marsching, Christian; Minta, Karolina; Ge, Junyue; Meyer, Sven W; Zetterberg, Henrik; Blennow, Kaj; Henkel, Corinna; Oetjen, Janina; Hopf, Carsten; Hanrieder, Jörg.
Affiliation
  • Michno W; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
  • Wehrli PM; Department of Neuroscience, Physiology and Pharmacology, University College London, Gower Street, London, UK.
  • Koutarapu S; Department of Pediatrics, Stanford University School of Medicine, Stanford University, Stanford, California, USA.
  • Marsching C; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
  • Minta K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
  • Ge J; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany.
  • Meyer SW; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
  • Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
  • Blennow K; Bruker Daltonics GmbH & Co. KG, Bremen, Germany.
  • Henkel C; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
  • Oetjen J; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital Mölndal, Mölndal, Sweden.
  • Hopf C; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK.
  • Hanrieder J; UK Dementia Research Institute, University College London, London, UK.
J Neurochem ; 160(4): 482-498, 2022 02.
Article in En | MEDLINE | ID: mdl-34882796
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Plaque, Amyloid / Lipid Metabolism / Neuroimaging Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: J Neurochem Year: 2022 Document type: Article Affiliation country: Suecia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Plaque, Amyloid / Lipid Metabolism / Neuroimaging Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: J Neurochem Year: 2022 Document type: Article Affiliation country: Suecia