The effects of lung involvement, clinical and laboratory parameters on outcome in elderly patients with coronavirus disease 2019.

ABSTRACT

We aimed to investigate the association of lung involvement and biochemical parameters with patients' demographic characteristics, and how this association effects the disease course and mortality in elderly patients diagnosed with coronavirus disease 2019 (COVID-19). Age, degree of pulmonary involvement, comorbidities, and biochemical parameters of 211 patients who were 60 years or older, diagnosed with COVID-19, and had lung involvement were analyzed. The effects of these parameters on ICU admission and mortality were investigated. Advanced age, severity of lung involvement, elevated D-dimer, ferritin, and fibrinogen levels, and a previous history ofchronic obstructive pulmonary disease (COPD)were significant for predicting ICU admission and mortality. Along with advanced age, both the severity of lung involvement and a history of COPD had major impact on mortality in the course of COVID-19.