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A peripheral lipid sensor GPR120 remotely contributes to suppression of PGD2-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus.
Iwasa, Kensuke; Yamamoto, Shinji; Yamashina, Kota; Yagishita-Kyo, Nan; Maruyama, Kei; Awaji, Takeo; Takei, Yoshinori; Hirasawa, Akira; Yoshikawa, Keisuke.
Affiliation
  • Iwasa K; Department of Pharmacology, Faculty of Medicine, Saitama Medical University, 38 Moro-hongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan.
  • Yamamoto S; Department of Pharmacology, Faculty of Medicine, Saitama Medical University, 38 Moro-hongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan.
  • Yamashina K; Department of Pharmacology, Faculty of Medicine, Saitama Medical University, 38 Moro-hongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan.
  • Yagishita-Kyo N; Department of Pharmacology, Faculty of Medicine, Saitama Medical University, 38 Moro-hongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan.
  • Maruyama K; Department of Pharmacology, Faculty of Medicine, Saitama Medical University, 38 Moro-hongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan.
  • Awaji T; Department of Pharmacology, Faculty of Medicine, Saitama Medical University, 38 Moro-hongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan.
  • Takei Y; Department of Translational Research and Cellular Therapeutics, School of Medicine, Faculty of Medicine, Toho University, 5-21-16 Omori-Nishi, Ota-ku, Tokyo, 143-8540, Japan.
  • Hirasawa A; Department of Genomic Drug Discovery Science, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimo-Adachi-cho, Sakyo-ku, Kyoto, 606-8501, Japan.
  • Yoshikawa K; Institute for Integrated Medical Sciences, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.
J Neuroinflammation ; 18(1): 304, 2021 Dec 27.
Article in En | MEDLINE | ID: mdl-34961526
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Suppression, Genetic / Prostaglandin D2 / Microglia / Neurodegenerative Diseases / Receptors, G-Protein-Coupled / Neuroinflammatory Diseases / Hippocampus Limits: Animals Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2021 Document type: Article Affiliation country: Japón
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Suppression, Genetic / Prostaglandin D2 / Microglia / Neurodegenerative Diseases / Receptors, G-Protein-Coupled / Neuroinflammatory Diseases / Hippocampus Limits: Animals Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2021 Document type: Article Affiliation country: Japón