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Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase.
Tang, Haoyu; Wu, Min-Hao; Lin, Hsiao-Yu; Han, Meng-Ru; Tu, Yueh-Hua; Yang, Zhi-Jie; Chien, Tun-Cheng; Chan, Nei-Li; Chang, Wei-Chen.
Affiliation
  • Tang H; Department of Chemistry, North Carolina State University, Raleigh, NC 27695.
  • Wu MH; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
  • Lin HY; Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
  • Han MR; Department of Chemistry, National Taiwan Normal University, Taipei 116, Taiwan.
  • Tu YH; Department of Chemistry, National Taiwan Normal University, Taipei 116, Taiwan.
  • Yang ZJ; Department of Chemistry, National Taiwan Normal University, Taipei 116, Taiwan.
  • Chien TC; Department of Chemistry, National Taiwan Normal University, Taipei 116, Taiwan; tcchien@ntnu.edu.tw nlchan@ntu.edu.tw wchang6@ncsu.edu.
  • Chan NL; Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
  • Chang WC; Faculty of Pharmacy, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Proc Natl Acad Sci U S A ; 119(1)2022 01 04.
Article in En | MEDLINE | ID: mdl-34969844
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Proteins / Podophyllotoxin / Drugs, Chinese Herbal / Berberidaceae / Ligases Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Proteins / Podophyllotoxin / Drugs, Chinese Herbal / Berberidaceae / Ligases Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Country of publication: Estados Unidos