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NUDT15 is a key genetic factor for prediction of hematotoxicity in pediatric patients who received a standard low dosage regimen of 6-mercaptopurine.
Khaeso, Kanyarat; Komvilaisak, Patcharee; Chainansamit, Su-On; Nakkam, Nontaya; Suwannaying, Kunanya; Kuwatjanakul, Pitchayanan; Hikino, Keiko; Dornsena, Areerat; Kanjanawart, Sirimas; Laoaroon, Napat; Vannaprasaht, Suda; Taketani, Takeshi; Tassaneeyakul, Wichittra.
Affiliation
  • Khaeso K; Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Thailand.
  • Komvilaisak P; Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Thailand.
  • Chainansamit SO; Department of Pediatrics, Khon Kaen Hospital, Khon Kaen, Thailand.
  • Nakkam N; Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Thailand.
  • Suwannaying K; Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Thailand.
  • Kuwatjanakul P; Department of Pediatrics, Udon Thani Hospital, Udon Thani, Thailand.
  • Hikino K; Laboratory for Pharmacogenomics, RIKEN Center for Integrative Medical Sciences, Yokohama City, Kanagawa, Japan.
  • Dornsena A; Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Thailand.
  • Kanjanawart S; Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Thailand.
  • Laoaroon N; Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Thailand.
  • Vannaprasaht S; Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Thailand.
  • Taketani T; Department of Pediatrics, Faculty of Medicine, Shimane University, Izumo, Japan.
  • Tassaneeyakul W; Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Thailand. Electronic address: wichitt@kku.ac.th.
Drug Metab Pharmacokinet ; 43: 100436, 2022 Apr.
Article in En | MEDLINE | ID: mdl-35016134
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor Cell Lymphoblastic Leukemia-Lymphoma / Mercaptopurine Type of study: Prognostic_studies / Risk_factors_studies Limits: Child / Humans Language: En Journal: Drug Metab Pharmacokinet Journal subject: FARMACOLOGIA / METABOLISMO Year: 2022 Document type: Article Affiliation country: Tailandia
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor Cell Lymphoblastic Leukemia-Lymphoma / Mercaptopurine Type of study: Prognostic_studies / Risk_factors_studies Limits: Child / Humans Language: En Journal: Drug Metab Pharmacokinet Journal subject: FARMACOLOGIA / METABOLISMO Year: 2022 Document type: Article Affiliation country: Tailandia