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A study on the processing technology for Rhizoma Coptidis.
Wang, Yunhong; Qin, Weihan; Yang, Yujie; Bai, Hui; Wang, Jirui; Zhang, Xiaomei; Guo, Yanlei; Hua, Lei; Yang, Yong.
Affiliation
  • Wang Y; Department of Institute of Pharmacochemistry of Traditional Chinese Medicine, Chongqing Academy of Chinese Materia Medica, No. 34 of Nanshan Street, Nanan District, Chongqing, 400065, China.
  • Qin W; Department of Institute of Pharmacochemistry of Traditional Chinese Medicine, Chongqing Academy of Chinese Materia Medica, No. 34 of Nanshan Street, Nanan District, Chongqing, 400065, China.
  • Yang Y; Chongqong University of Education, Chongqing, 400067, China.
  • Bai H; Chongqong University of Education, Chongqing, 400067, China.
  • Wang J; Department of Institute of Pharmacochemistry of Traditional Chinese Medicine, Chongqing Academy of Chinese Materia Medica, No. 34 of Nanshan Street, Nanan District, Chongqing, 400065, China.
  • Zhang X; Department of Institute of Pharmacochemistry of Traditional Chinese Medicine, Chongqing Academy of Chinese Materia Medica, No. 34 of Nanshan Street, Nanan District, Chongqing, 400065, China.
  • Guo Y; Department of Institute of Pharmacochemistry of Traditional Chinese Medicine, Chongqing Academy of Chinese Materia Medica, No. 34 of Nanshan Street, Nanan District, Chongqing, 400065, China.
  • Hua L; Department of Institute of Pharmacochemistry of Traditional Chinese Medicine, Chongqing Academy of Chinese Materia Medica, No. 34 of Nanshan Street, Nanan District, Chongqing, 400065, China.
  • Yang Y; Department of Institute of Pharmacochemistry of Traditional Chinese Medicine, Chongqing Academy of Chinese Materia Medica, No. 34 of Nanshan Street, Nanan District, Chongqing, 400065, China. yangyongk291@163.com.
BMC Biotechnol ; 22(1): 3, 2022 01 14.
Article in En | MEDLINE | ID: mdl-35031033
ABSTRACT

BACKGROUND:

The present study intends to optimize the processing technology for the wine-processing of Rhizoma Coptidis, using alkaloids as indicators.

METHOD:

In the present study, the Box-Behnken design method was adopted to optimize the processing technology for Rhizoma Coptidis, using the alkaloid component quantities as the index. 100 g of Rhizoma Coptidis slices and 12.5 g of Rhizoma Coptidis wine were used. After full mixing, box-Behnken design method was used to optimize the processing time, processing temperature and processing time of coptis chinensis by taking alkaloid content as index. After mixing well, these components were fried in a container at 125 °C for 6 min and exhibited good parallelism.

RESULTS:

The content of alkaloids in coptis chinensis was the highest after roasting at 125 °C for 6 min. The characteristic components were berberine hydrochloride, and the relative content was about 15.96%. And showed good parallelism. The effective components of Rhizoma Coptidis were primarily alkaloids.

CONCLUSION:

The optimized processing technology for Rhizoma Coptidis is good.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drugs, Chinese Herbal / Coptis / Alkaloids Language: En Journal: BMC Biotechnol Journal subject: BIOTECNOLOGIA Year: 2022 Document type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drugs, Chinese Herbal / Coptis / Alkaloids Language: En Journal: BMC Biotechnol Journal subject: BIOTECNOLOGIA Year: 2022 Document type: Article Affiliation country: China