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A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in mice.
Lazo, Laura; Bequet-Romero, Monica; Lemos, Gilda; Musacchio, Alexis; Cabrales, Ania; Bruno, Andy J; Ariel Espinosa, Luis; Saloheimo, Markku; Vitikainen, Marika; Hernández, Amalia; Emalfarb, Mark; Tchelet, Ronen; Suzarte, Edith; Guillén, Gerardo.
Affiliation
  • Lazo L; Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box. 6162, Havana 6 10600, Cuba. Electronic address: laura.lazo@cigb.edu.cu.
  • Bequet-Romero M; Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box. 6162, Havana 6 10600, Cuba.
  • Lemos G; Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box. 6162, Havana 6 10600, Cuba.
  • Musacchio A; Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box. 6162, Havana 6 10600, Cuba.
  • Cabrales A; Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box. 6162, Havana 6 10600, Cuba.
  • Bruno AJ; Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box. 6162, Havana 6 10600, Cuba.
  • Ariel Espinosa L; Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box. 6162, Havana 6 10600, Cuba.
  • Saloheimo M; VTT Technical Research Centre of Finland Ltd., P.O. Box 1000, 02044 VTT (Espoo), Finland.
  • Vitikainen M; VTT Technical Research Centre of Finland Ltd., P.O. Box 1000, 02044 VTT (Espoo), Finland.
  • Hernández A; Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box. 6162, Havana 6 10600, Cuba.
  • Emalfarb M; Dyadic International, Inc, 140 Intracoastal Pointe Drive, Suite 404, Jupiter, FL 33477, United States.
  • Tchelet R; Dyadic International, Inc, 140 Intracoastal Pointe Drive, Suite 404, Jupiter, FL 33477, United States.
  • Suzarte E; Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box. 6162, Havana 6 10600, Cuba.
  • Guillén G; Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box. 6162, Havana 6 10600, Cuba.
Vaccine ; 40(8): 1162-1169, 2022 02 16.
Article in En | MEDLINE | ID: mdl-35078661
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spike Glycoprotein, Coronavirus / COVID-19 Limits: Animals / Humans Language: En Journal: Vaccine Year: 2022 Document type: Article Country of publication: Países Bajos
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spike Glycoprotein, Coronavirus / COVID-19 Limits: Animals / Humans Language: En Journal: Vaccine Year: 2022 Document type: Article Country of publication: Países Bajos