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Classical RAS proteins are not essential for paradoxical ERK activation induced by RAF inhibitors.
Lai, Lick Pui; Fer, Nicole; Burgan, William; Wall, Vanessa E; Xu, Bingfang; Soppet, Daniel; Esposito, Dominic; Nissley, Dwight V; McCormick, Frank.
Affiliation
  • Lai LP; RAS initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702; licklai@ymail.com frank.mccormick@ucsf.edu.
  • Fer N; RAS initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702.
  • Burgan W; RAS initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702.
  • Wall VE; RAS initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702.
  • Xu B; RAS initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702.
  • Soppet D; RAS initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702.
  • Esposito D; RAS initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702.
  • Nissley DV; RAS initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702.
  • McCormick F; RAS initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702; licklai@ymail.com frank.mccormick@ucsf.edu.
Proc Natl Acad Sci U S A ; 119(5)2022 02 01.
Article in En | MEDLINE | ID: mdl-35091470
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ras Proteins / MAP Kinase Signaling System / Raf Kinases Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ras Proteins / MAP Kinase Signaling System / Raf Kinases Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Country of publication: Estados Unidos