Function of m6A and its regulation of domesticated animals' complex traits.
J Anim Sci
; 100(3)2022 Mar 01.
Article
in En
| MEDLINE
| ID: mdl-35137116
N6-methyladenosine (m6A) is the most abundant RNA modification in eukaryotes. Current studies showed that the m6A modification widely regulates a series of life processes, such as biological metabolism, growth and development, inflammation, and cancer. Understanding the m6A process of domestic animals can provide a new breakthrough for further promoting animal production performance and improving reproduction and disease resistance. Thus, this review briefly introduces m6A-related enzymes, m6A detection technologies, small-molecule inhibitors of m6A-related enzymes, and interaction between m6A and other biological progresses. In addition, the regulation mechanisms of m6A in domesticated animals' complex traits are elaborated and discussed.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Multifactorial Inheritance
/
Animals, Domestic
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
J Anim Sci
Year:
2022
Document type:
Article
Affiliation country:
China
Country of publication:
Estados Unidos