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Platelet CFTR inhibition enhances arterial thrombosis via increasing intracellular Cl- concentration and activation of SGK1 signaling pathway.
Yang, Han-Yan; Zhang, Chao; Hu, Liang; Liu, Chang; Pan, Ni; Li, Mei; Han, Hui; Zhou, Yi; Li, Jie; Zhao, Li-Yan; Liu, Yao-Sheng; Luo, Bing-Zheng; Huang, Xiong-Qing; Lv, Xiao-Fei; Li, Zi-Cheng; Li, Jun; Li, Zhi-Hong; Wang, Ruo-Mei; Wang, Li; Guan, Yong-Yuan; Liu, Can-Zhao; Zhang, Bin; Wang, Guan-Lei.
Affiliation
  • Yang HY; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Zhang C; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Hu L; Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
  • Liu C; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Pan N; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Li M; Institute of Pediatrics, Guangzhou Women and Children's Medical Center affiliated to Guangzhou Medical College, Guangzhou, 510623, China.
  • Han H; VIP Healthcare Center, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, China.
  • Zhou Y; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Li J; Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.
  • Zhao LY; Department of Anesthesiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
  • Liu YS; Department of Pharmacy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
  • Luo BZ; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Huang XQ; Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.
  • Lv XF; Department of Anesthesiology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China.
  • Li ZC; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Li J; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Li ZH; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Wang RM; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Wang L; School of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, 510006, China.
  • Guan YY; Division of Biological Sciences, University of California, San Diego, La Jolla, CA, USA.
  • Liu CZ; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
  • Zhang B; Department of Cardiovascular Medicine, Translational Medicine Research Center, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China. liucanzhao0521@163.com.
  • Wang GL; Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. drbinzhang@gdph.org.cn.
Acta Pharmacol Sin ; 43(10): 2596-2608, 2022 Oct.
Article in En | MEDLINE | ID: mdl-35241769
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Immediate-Early Proteins / Cystic Fibrosis Transmembrane Conductance Regulator Type of study: Prognostic_studies Limits: Animals Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2022 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Immediate-Early Proteins / Cystic Fibrosis Transmembrane Conductance Regulator Type of study: Prognostic_studies Limits: Animals Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2022 Document type: Article Affiliation country: China