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Whole-genome sequencing reveals host factors underlying critical COVID-19.
Kousathanas, Athanasios; Pairo-Castineira, Erola; Rawlik, Konrad; Stuckey, Alex; Odhams, Christopher A; Walker, Susan; Russell, Clark D; Malinauskas, Tomas; Wu, Yang; Millar, Jonathan; Shen, Xia; Elliott, Katherine S; Griffiths, Fiona; Oosthuyzen, Wilna; Morrice, Kirstie; Keating, Sean; Wang, Bo; Rhodes, Daniel; Klaric, Lucija; Zechner, Marie; Parkinson, Nick; Siddiq, Afshan; Goddard, Peter; Donovan, Sally; Maslove, David; Nichol, Alistair; Semple, Malcolm G; Zainy, Tala; Maleady-Crowe, Fiona; Todd, Linda; Salehi, Shahla; Knight, Julian; Elgar, Greg; Chan, Georgia; Arumugam, Prabhu; Patch, Christine; Rendon, Augusto; Bentley, David; Kingsley, Clare; Kosmicki, Jack A; Horowitz, Julie E; Baras, Aris; Abecasis, Goncalo R; Ferreira, Manuel A R; Justice, Anne; Mirshahi, Tooraj; Oetjens, Matthew; Rader, Daniel J; Ritchie, Marylyn D; Verma, Anurag.
Affiliation
  • Kousathanas A; Genomics England, London, UK.
  • Pairo-Castineira E; Roslin Institute, University of Edinburgh, Edinburgh, UK.
  • Rawlik K; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK.
  • Stuckey A; Roslin Institute, University of Edinburgh, Edinburgh, UK.
  • Odhams CA; Genomics England, London, UK.
  • Walker S; Genomics England, London, UK.
  • Russell CD; Genomics England, London, UK.
  • Malinauskas T; Roslin Institute, University of Edinburgh, Edinburgh, UK.
  • Wu Y; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
  • Millar J; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Shen X; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
  • Elliott KS; Roslin Institute, University of Edinburgh, Edinburgh, UK.
  • Griffiths F; Biostatistics Group, Greater Bay Area Institute of Precision Medicine (Guangzhou), Fudan University, Guangzhou, China.
  • Oosthuyzen W; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, Edinburgh, UK.
  • Morrice K; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Keating S; Roslin Institute, University of Edinburgh, Edinburgh, UK.
  • Wang B; Roslin Institute, University of Edinburgh, Edinburgh, UK.
  • Rhodes D; Edinburgh Clinical Research Facility, Western General Hospital, University of Edinburgh, Edinburgh, UK.
  • Klaric L; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
  • Zechner M; Roslin Institute, University of Edinburgh, Edinburgh, UK.
  • Parkinson N; Genomics England, London, UK.
  • Siddiq A; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK.
  • Goddard P; Roslin Institute, University of Edinburgh, Edinburgh, UK.
  • Donovan S; Roslin Institute, University of Edinburgh, Edinburgh, UK.
  • Maslove D; Genomics England, London, UK.
  • Nichol A; Genomics England, London, UK.
  • Semple MG; Genomics England, London, UK.
  • Zainy T; Department of Critical Care Medicine, Queen's University and Kingston Health Sciences Centre, Kingston, Ontario, Canada.
  • Maleady-Crowe F; Clinical Research Centre at St Vincent's University Hospital, University College Dublin, Dublin, Ireland.
  • Todd L; NIHR Health Protection Research Unit for Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
  • Salehi S; Respiratory Medicine and Institute in the Park, Alder Hey Children's Hospital and University of Liverpool, Liverpool, UK.
  • Knight J; Genomics England, London, UK.
  • Elgar G; Genomics England, London, UK.
  • Chan G; Genomics England, London, UK.
  • Arumugam P; Genomics England, London, UK.
  • Patch C; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Rendon A; Genomics England, London, UK.
  • Bentley D; Genomics England, London, UK.
  • Kingsley C; Genomics England, London, UK.
  • Kosmicki JA; Genomics England, London, UK.
  • Horowitz JE; Genomics England, London, UK.
  • Baras A; Illumina Cambridge, Great Abington, UK.
  • Abecasis GR; Illumina Cambridge, Great Abington, UK.
  • Ferreira MAR; Regeneron Genetics Center, Tarrytown, NY, USA.
  • Justice A; Regeneron Genetics Center, Tarrytown, NY, USA.
  • Mirshahi T; Regeneron Genetics Center, Tarrytown, NY, USA.
  • Oetjens M; Regeneron Genetics Center, Tarrytown, NY, USA.
  • Rader DJ; Regeneron Genetics Center, Tarrytown, NY, USA.
  • Ritchie MD; Geisinger, Danville, PA, USA.
  • Verma A; Geisinger, Danville, PA, USA.
Nature ; 607(7917): 97-103, 2022 07.
Article in En | MEDLINE | ID: mdl-35255492
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome, Human / Critical Illness / Host-Pathogen Interactions / Whole Genome Sequencing / COVID-19 Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2022 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome, Human / Critical Illness / Host-Pathogen Interactions / Whole Genome Sequencing / COVID-19 Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2022 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido