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Pharmacokinetics of ß-d-N4-Hydroxycytidine, the Parent Nucleoside of Prodrug Molnupiravir, in Nonplasma Compartments of Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
FitzGerald, Richard; Dickinson, Laura; Else, Laura; Fletcher, Thomas; Hale, Colin; Amara, Alieu; Walker, Lauren; Penchala, Sujan Dilly; Lyon, Rebecca; Shaw, Victoria; Greenhalf, William; Bullock, Katie; Lavelle-Langham, Lara; Reynolds, Helen; Painter, Wendy; Holman, Wayne; Ewings, Sean; Griffiths, Gareth; Khoo, Saye.
Affiliation
  • FitzGerald R; National Institute for Health Research Royal Liverpool & Broadgreen Clinical Research Facility, Liverpool University Hospital NHS Foundation Trust, Liverpool, United Kingdom.
  • Dickinson L; Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom.
  • Else L; Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom.
  • Fletcher T; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Hale C; National Institute for Health Research Royal Liverpool & Broadgreen Clinical Research Facility, Liverpool University Hospital NHS Foundation Trust, Liverpool, United Kingdom.
  • Amara A; Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom.
  • Walker L; National Institute for Health Research Royal Liverpool & Broadgreen Clinical Research Facility, Liverpool University Hospital NHS Foundation Trust, Liverpool, United Kingdom.
  • Penchala SD; Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom.
  • Lyon R; National Institute for Health Research Royal Liverpool & Broadgreen Clinical Research Facility, Liverpool University Hospital NHS Foundation Trust, Liverpool, United Kingdom.
  • Shaw V; Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom.
  • Greenhalf W; Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom.
  • Bullock K; Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom.
  • Lavelle-Langham L; Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom.
  • Reynolds H; Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom.
  • Painter W; Ridgeback Biotherapeutics, Miami, Florida, USA.
  • Holman W; Ridgeback Biotherapeutics, Miami, Florida, USA.
  • Ewings S; National Institute for Health Research Southampton Clinical Trials Unit, University of Southampton, Southampton, United Kingdom.
  • Griffiths G; National Institute for Health Research Southampton Clinical Trials Unit, University of Southampton, Southampton, United Kingdom.
  • Khoo S; National Institute for Health Research Royal Liverpool & Broadgreen Clinical Research Facility, Liverpool University Hospital NHS Foundation Trust, Liverpool, United Kingdom.
Clin Infect Dis ; 75(1): e525-e528, 2022 08 24.
Article in En | MEDLINE | ID: mdl-35271729
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / COVID-19 Drug Treatment Limits: Humans Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2022 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / COVID-19 Drug Treatment Limits: Humans Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2022 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos