Korean Guidelines for Pharmacoeconomic Evaluations: Updates in the Third Version.
Appl Health Econ Health Policy
; 20(4): 467-477, 2022 07.
Article
in En
| MEDLINE
| ID: mdl-35275388
ABSTRACT
The first version of the pharmacoeconomic (PE) guidelines was published in South Korea in 2006. Despite its first revision in 2011, there were still ambiguities in its interpretation. Moreover, methodologies for estimating effectiveness and costs have also evolved since then. Under these circumstances, the Health Insurance Review and Assessment Service published the third version in January 2021. This article reviews the revision process and major changes made in the new edition of the PE guidelines. The revision was processed through reviews of the previous 50 PE submissions, international guidelines, academic literature, and surveys and advisory meetings to obtain stakeholders' opinions. The analysis perspective has changed from a limited societal perspective to a healthcare system perspective. In addition to the drug with the highest market share, drugs used in clinical trials can be selected as comparators under certain conditions. The discount rate decreased from 5% to 4.5%. Furthermore, the revised guidelines provide more detailed and specific instructions for items including non-inferiority margin, extrapolation, utility elicitation, and uncertainty. Treatment switch and co-dependent technology guidelines are newly included; the budget impact analysis guideline is deleted. Through this revision, transparency and consistency of decision-making is expected to improve.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Budgets
/
Economics, Pharmaceutical
Type of study:
Guideline
/
Health_economic_evaluation
/
Prognostic_studies
/
Qualitative_research
Limits:
Humans
Language:
En
Journal:
Appl Health Econ Health Policy
Journal subject:
SAUDE PUBLICA
/
SERVICOS DE SAUDE
Year:
2022
Document type:
Article
Affiliation country:
Corea del Sur