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Exploring the safety, effect on the tumor microenvironment, and efficacy of itacitinib in combination with epacadostat or parsaclisib in advanced solid tumors: a phase I study.
Naing, Aung; Powderly, John D; Nemunaitis, John J; Luke, Jason J; Mansfield, Aaron S; Messersmith, Wells A; Sahebjam, Solmaz; LoRusso, Patricia M; Garrido-Laguna, Ignacio; Leopold, Lance; Geschwindt, Ryan; Ding, Kai; Smith, Michael; Berlin, Jordan D.
Affiliation
  • Naing A; Department of Investigational Cancer Therapeutics, MD Anderson Cancer Center, Houston, Texas, USA anaing@mdanderson.org.
  • Powderly JD; Cancer Research Clinic, Carolina Biooncology Institute, Huntersville, North Carolina, USA.
  • Nemunaitis JJ; University of Toledo College of Medicine, Toledo, Ohio, USA.
  • Luke JJ; Division of Hematology/Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
  • Mansfield AS; Oncology, Mayo Clinic, Rochester, Minnesota, USA.
  • Messersmith WA; School of Medicine, University of Colorado, Aurora, Colorado, USA.
  • Sahebjam S; Clinical Research Unit, Moffitt Cancer Center, Tampa, Florida, USA.
  • LoRusso PM; Yale School of Medicine, Yale Cancer Center, New Haven, Connecticut, USA.
  • Garrido-Laguna I; University of Utah School of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah, USA.
  • Leopold L; Immuno-Oncology, Incyte Corporation, Wilmington, Delaware, USA.
  • Geschwindt R; Immuno-Oncology, Incyte Corporation, Wilmington, Delaware, USA.
  • Ding K; Biostatistics, Incyte Corporation, Wilmington, Delaware, USA.
  • Smith M; Immuno-Oncology, Incyte Corporation, Wilmington, Delaware, USA.
  • Berlin JD; Division of Hematology/Oncology, Vanderbilt University, Nashville, Tennessee, USA.
J Immunother Cancer ; 10(3)2022 03.
Article in En | MEDLINE | ID: mdl-35288468
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Microenvironment / Neoplasms Type of study: Clinical_trials Limits: Humans Language: En Journal: J Immunother Cancer Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Microenvironment / Neoplasms Type of study: Clinical_trials Limits: Humans Language: En Journal: J Immunother Cancer Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido