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Clinical characteristics of adults suffering from high-functioning autism and comorbid obsessive-compulsive disorder.
Lamothe, Hugues; Godin, Ophélia; Stengel, Chloé; Benmansour, Safiyah; Burckard, Soline; Brouillet Z, Julie; Petrucci, Jean; Weil, Delphine; Lejuste, Florian; Leboyer, Marion.
Affiliation
  • Lamothe H; Sorbonne University, Brain and Spine Institute, INSERM UMR_S 1127/UMR 7225, 57 boulevard de l'hôpital, 75013 Paris, France; AP-HP, Albert Chenevier University Hospital, University Paris Est Créteil, 40 rue de Mesly, 94000 Créteil, France. Electronic address: lamothehugues@gmail.com.
  • Godin O; AP-HP, Albert Chenevier University Hospital, University Paris Est Créteil, 40 rue de Mesly, 94000 Créteil, France; University Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, AP-HP, DMU IMPACT, FHU ADAPT, Fondation FondaMental, F-94010, Créteil, France.
  • Stengel C; Sorbonne University, Brain and Spine Institute, INSERM UMR_S 1127/UMR 7225, 57 boulevard de l'hôpital, 75013 Paris, France.
  • Benmansour S; AP-HP, Albert Chenevier University Hospital, University Paris Est Créteil, 40 rue de Mesly, 94000 Créteil, France; University Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, AP-HP, DMU IMPACT, FHU ADAPT, Fondation FondaMental, F-94010, Créteil, France.
  • Burckard S; AP-HP, Albert Chenevier University Hospital, University Paris Est Créteil, 40 rue de Mesly, 94000 Créteil, France; University Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, AP-HP, DMU IMPACT, FHU ADAPT, Fondation FondaMental, F-94010, Créteil, France.
  • Brouillet Z J; University Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, AP-HP, DMU IMPACT, FHU ADAPT, Fondation FondaMental, F-94010, Créteil, France.
  • Petrucci J; AP-HP, Albert Chenevier University Hospital, University Paris Est Créteil, 40 rue de Mesly, 94000 Créteil, France; University Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, AP-HP, DMU IMPACT, FHU ADAPT, Fondation FondaMental, F-94010, Créteil, France.
  • Weil D; AP-HP, Albert Chenevier University Hospital, University Paris Est Créteil, 40 rue de Mesly, 94000 Créteil, France; University Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, AP-HP, DMU IMPACT, FHU ADAPT, Fondation FondaMental, F-94010, Créteil, France.
  • Lejuste F; AP-HP, Albert Chenevier University Hospital, University Paris Est Créteil, 40 rue de Mesly, 94000 Créteil, France; University Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, AP-HP, DMU IMPACT, FHU ADAPT, Fondation FondaMental, F-94010, Créteil, France.
  • Leboyer M; AP-HP, Albert Chenevier University Hospital, University Paris Est Créteil, 40 rue de Mesly, 94000 Créteil, France; University Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, AP-HP, DMU IMPACT, FHU ADAPT, Fondation FondaMental, F-94010, Créteil, France.
Psychiatry Res ; 311: 114498, 2022 05.
Article in En | MEDLINE | ID: mdl-35290885
ABSTRACT
Autism spectrum disorder (ASD) is a very heterogeneous disorder. Obsessive compulsive disorder (OCD) comorbidity, frequent in ASD, could be useful to define a specific ASD subtype. Our objective was to explore if adults with ASD and comorbid OCD could present a specific clinical profile of ASD in 89 high functioning-adult ASD patients. We found that adults with ASD and comorbid OCD showed a lower verbal IQ and a more severe impairments in social cognition. ASD with comorbid OCD present a specific clinical profile which could constitute a possible subtype of ASD.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autism Spectrum Disorder / Obsessive-Compulsive Disorder Limits: Adult / Humans Language: En Journal: Psychiatry Res Year: 2022 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autism Spectrum Disorder / Obsessive-Compulsive Disorder Limits: Adult / Humans Language: En Journal: Psychiatry Res Year: 2022 Document type: Article