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Astegolimab, an anti-ST2, in chronic obstructive pulmonary disease (COPD-ST2OP): a phase 2a, placebo-controlled trial.
Yousuf, Ahmed J; Mohammed, Seid; Carr, Liesl; Yavari Ramsheh, Mohammadali; Micieli, Claudia; Mistry, Vijay; Haldar, Kairobi; Wright, Adam; Novotny, Petr; Parker, Sarah; Glover, Sarah; Finch, Joanne; Quann, Niamh; Brookes, Cassandra L; Hobson, Rachel; Ibrahim, Wadah; Russell, Richard J; John, Catherine; Grimbaldeston, Michele A; Choy, David F; Cheung, Dorothy; Steiner, Michael; Greening, Neil J; Brightling, Christopher E.
Affiliation
  • Yousuf AJ; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Mohammed S; Leicester Clinical Trials Unit, College of Life Sciences, University of Leicester, Leicester, UK.
  • Carr L; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Yavari Ramsheh M; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Micieli C; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Mistry V; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Haldar K; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Wright A; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Novotny P; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Parker S; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Glover S; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Finch J; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Quann N; Leicester Clinical Trials Unit, College of Life Sciences, University of Leicester, Leicester, UK.
  • Brookes CL; Leicester Clinical Trials Unit, College of Life Sciences, University of Leicester, Leicester, UK.
  • Hobson R; Leicester Clinical Trials Unit, College of Life Sciences, University of Leicester, Leicester, UK.
  • Ibrahim W; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Russell RJ; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • John C; Department of Health Sciences, University of Leicester, Leicester, UK.
  • Grimbaldeston MA; Genentech, San Francisco, CA, USA.
  • Choy DF; Genentech, San Francisco, CA, USA.
  • Cheung D; Genentech, San Francisco, CA, USA.
  • Steiner M; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Greening NJ; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK.
  • Brightling CE; Institute for Lung Health, National Institute for Health Research Biomedical Research Centre Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, UK. Electronic address: ceb17@le.ac.uk.
Lancet Respir Med ; 10(5): 469-477, 2022 05.
Article in En | MEDLINE | ID: mdl-35339234
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Disease, Chronic Obstructive / Interleukin-1 Receptor-Like 1 Protein Type of study: Clinical_trials / Prognostic_studies Aspects: Patient_preference Limits: Humans Language: En Journal: Lancet Respir Med Year: 2022 Document type: Article Country of publication: Reino Unido
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Disease, Chronic Obstructive / Interleukin-1 Receptor-Like 1 Protein Type of study: Clinical_trials / Prognostic_studies Aspects: Patient_preference Limits: Humans Language: En Journal: Lancet Respir Med Year: 2022 Document type: Article Country of publication: Reino Unido