Necrotizing enterovirus myositis in a pediatric renal transplant recipient.
Pediatr Transplant
; 26(5): e14275, 2022 08.
Article
in En
| MEDLINE
| ID: mdl-35340121
ABSTRACT
BACKGROUND:
Enteroviruses can cause severe infections, including viral myocarditis, meningitis, acute flaccid myelitis, and viral myositis. METHODS/RESULTS:
We report a 3-year-old female renal transplant recipient who presented to a tertiary care hospital with elevated serum liver aminotransferases and subsequently developed proximal muscle pain, weakness, and respiratory distress during the first week of hospitalization. Imaging of the lower extremities revealed diffuse myositis of the proximal thigh and pelvic muscles. A muscle biopsy was obtained and revealed necrotizing myositis with immunostaining positive for enterovirus, consistent with a diagnosis of enterovirus necrotizing myositis. She had complete resolution of symptoms with steroids, intravenous immune globulin, reduced tacrolimus dose, and physical therapy.CONCLUSIONS:
Enterovirus myositis should be included in the differential diagnosis for necrotizing myositis following renal transplantation in children.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Kidney Transplantation
/
Enterovirus
/
Fasciitis, Necrotizing
/
Enterovirus Infections
/
Myelitis
/
Myositis
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Child
/
Child, preschool
/
Female
/
Humans
Language:
En
Journal:
Pediatr Transplant
Journal subject:
PEDIATRIA
/
TRANSPLANTE
Year:
2022
Document type:
Article
Affiliation country:
Estados Unidos