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Improved Digital Therapy for Developmental Pediatrics Using Domain-Specific Artificial Intelligence: Machine Learning Study.
Washington, Peter; Kalantarian, Haik; Kent, John; Husic, Arman; Kline, Aaron; Leblanc, Emilie; Hou, Cathy; Mutlu, Onur Cezmi; Dunlap, Kaitlyn; Penev, Yordan; Varma, Maya; Stockham, Nate Tyler; Chrisman, Brianna; Paskov, Kelley; Sun, Min Woo; Jung, Jae-Yoon; Voss, Catalin; Haber, Nick; Wall, Dennis Paul.
Affiliation
  • Washington P; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Kalantarian H; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Kent J; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Husic A; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Kline A; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Leblanc E; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Hou C; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Mutlu OC; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Dunlap K; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Penev Y; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Varma M; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Stockham NT; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Chrisman B; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Paskov K; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Sun MW; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Jung JY; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Voss C; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Haber N; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
  • Wall DP; Departments of Pediatrics (Systems Medicine) and Biomedical Data Science, Stanford University, Stanford, CA, United States.
JMIR Pediatr Parent ; 5(2): e26760, 2022 Apr 08.
Article in En | MEDLINE | ID: mdl-35394438
ABSTRACT

BACKGROUND:

Automated emotion classification could aid those who struggle to recognize emotions, including children with developmental behavioral conditions such as autism. However, most computer vision emotion recognition models are trained on adult emotion and therefore underperform when applied to child faces.

OBJECTIVE:

We designed a strategy to gamify the collection and labeling of child emotion-enriched images to boost the performance of automatic child emotion recognition models to a level closer to what will be needed for digital health care approaches.

METHODS:

We leveraged our prototype therapeutic smartphone game, GuessWhat, which was designed in large part for children with developmental and behavioral conditions, to gamify the secure collection of video data of children expressing a variety of emotions prompted by the game. Independently, we created a secure web interface to gamify the human labeling effort, called HollywoodSquares, tailored for use by any qualified labeler. We gathered and labeled 2155 videos, 39,968 emotion frames, and 106,001 labels on all images. With this drastically expanded pediatric emotion-centric database (>30 times larger than existing public pediatric emotion data sets), we trained a convolutional neural network (CNN) computer vision classifier of happy, sad, surprised, fearful, angry, disgust, and neutral expressions evoked by children.

RESULTS:

The classifier achieved a 66.9% balanced accuracy and 67.4% F1-score on the entirety of the Child Affective Facial Expression (CAFE) as well as a 79.1% balanced accuracy and 78% F1-score on CAFE Subset A, a subset containing at least 60% human agreement on emotions labels. This performance is at least 10% higher than all previously developed classifiers evaluated against CAFE, the best of which reached a 56% balanced accuracy even when combining "anger" and "disgust" into a single class.

CONCLUSIONS:

This work validates that mobile games designed for pediatric therapies can generate high volumes of domain-relevant data sets to train state-of-the-art classifiers to perform tasks helpful to precision health efforts.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: JMIR Pediatr Parent Year: 2022 Document type: Article Affiliation country: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: JMIR Pediatr Parent Year: 2022 Document type: Article Affiliation country: Estados Unidos