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ON-ICE trial: Investigation of the combined effects of oxytocin and naltrexone on stress-induced and alcohol cue-induced craving in alcohol use disorder-Study protocol of a phase II randomised double-blind placebo-controlled parallel-group trial.
Zimmermann, Sina; Thomas, Bettina C; Krisam, Johannes; Limprecht, Ronald; Klose, Christina; Stenger, Manuel; Pourbaix, Madeleine; Ries, Marcel; Vollstaedt-Klein, Sabine; Koopmann, Anne; Lenz, Bernd; Kiefer, Falk; Bach, Patrick.
Affiliation
  • Zimmermann S; Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany sina.zimmermann@zi-mannheim.de.
  • Thomas BC; Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany.
  • Krisam J; Coordination Centre for Clinical Trials (KKS), Medical Faculty, University Hospital Heidelberg, Heidelberg, Germany.
  • Limprecht R; Institute of Medical Biometry (IMBI), University of Heidelberg, Heidelberg, Germany.
  • Klose C; Institute of Medical Biometry (IMBI), University of Heidelberg, Heidelberg, Germany.
  • Stenger M; Institute of Medical Biometry (IMBI), University of Heidelberg, Heidelberg, Germany.
  • Pourbaix M; Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany.
  • Ries M; Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany.
  • Vollstaedt-Klein S; Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany.
  • Koopmann A; Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany.
  • Lenz B; Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany.
  • Kiefer F; Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany.
  • Bach P; Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany.
BMJ Open ; 12(4): e059672, 2022 04 11.
Article in En | MEDLINE | ID: mdl-35410938
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alcoholism / Naltrexone Type of study: Clinical_trials Aspects: Ethics Limits: Humans Language: En Journal: BMJ Open Year: 2022 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alcoholism / Naltrexone Type of study: Clinical_trials Aspects: Ethics Limits: Humans Language: En Journal: BMJ Open Year: 2022 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido