Imaging of the skin microvascularization using spatially depolarized dynamic speckle.
J Biomed Opt
; 27(4)2022 04.
Article
in En
| MEDLINE
| ID: mdl-35478040
ABSTRACT
SIGNIFICANCE:
We propose a technique devoted to real-time high-resolution imaging of skin microvascularization.AIM:
The process utilizes the temporal variation of the spatially depolarized optical speckle field generated by moving red blood cells when illuminated with fully polarized coherent light.APPROACH:
Polarimetric filtering prevents the contribution of surface scattering from reaching the camera and thus favors the detection of multiscattered photons from the deeper layers of the skin.RESULTS:
Full-field images reveal the microvasculature with a spatial resolution of 80 µm. The acquisition speed allows for real-time applications.CONCLUSIONS:
We demonstrate the ability of this method to determine in 1 s a stable and reliable microvascular activity, enabling numerous clinical applications that require quantitative measurements.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin
/
Diagnostic Imaging
Type of study:
Diagnostic_studies
Language:
En
Journal:
J Biomed Opt
Journal subject:
ENGENHARIA BIOMEDICA
/
OFTALMOLOGIA
Year:
2022
Document type:
Article
Affiliation country:
Francia