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Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors.
Parkhurst, Ashlyn; Wang, Sabrina Z; Findlay, Tyler R; Malebranche, Kristen J; Odabas, Arman; Alt, Jesse; Maxwell, Micah J; Kaur, Harpreet; Peer, Cody J; Figg, William D; Warren, Katherine E; Slusher, Barbara S; Eberhart, Charles G; Raabe, Eric H; Rubens, Jeffrey A.
Affiliation
  • Parkhurst A; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Wang SZ; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Findlay TR; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Malebranche KJ; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Odabas A; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Alt J; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Maxwell MJ; Division of Cell Biology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Kaur H; Clinical Pharmacology Program, National Cancer Institute at the National Institutes of Health, 37 Convent Dr, Bethesda, MD, 20892, USA.
  • Peer CJ; Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Figg WD; Department of Neurology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Warren KE; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Slusher BS; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Eberhart CG; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Raabe EH; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
  • Rubens JA; Clinical Pharmacology Program, National Cancer Institute at the National Institutes of Health, 37 Convent Dr, Bethesda, MD, 20892, USA.
Cell Death Dis ; 13(4): 410, 2022 04 28.
Article in En | MEDLINE | ID: mdl-35484114
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhabdoid Tumor Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Death Dis Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhabdoid Tumor Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Death Dis Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido