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The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62.
Linares, Juan F; Cid-Diaz, Tania; Duran, Angeles; Osrodek, Marta; Martinez-Ordoñez, Anxo; Reina-Campos, Miguel; Kuo, Hui-Hsuan; Elemento, Olivier; Martin, M Laura; Cordes, Thekla; Thompson, Timothy C; Metallo, Christian M; Moscat, Jorge; Diaz-Meco, Maria T.
Affiliation
  • Linares JF; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Cid-Diaz T; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Duran A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Osrodek M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Martinez-Ordoñez A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Reina-Campos M; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Kuo HH; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Elemento O; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Martin ML; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Cordes T; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
  • Thompson TC; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Metallo CM; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Moscat J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: jom4010@med.cornell.edu.
  • Diaz-Meco MT; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: mtd4001@med.cornell.edu.
Cell Rep ; 39(6): 110792, 2022 05 10.
Article in En | MEDLINE | ID: mdl-35545049
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cancer-Associated Fibroblasts / Neoplasms Type of study: Risk_factors_studies Language: En Journal: Cell Rep Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cancer-Associated Fibroblasts / Neoplasms Type of study: Risk_factors_studies Language: En Journal: Cell Rep Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos