A Case of COL1A1-PDGFB Fusion Uterine Sarcoma.
Int J Gynecol Pathol
; 42(2): 147-150, 2023 Mar 01.
Article
in En
| MEDLINE
| ID: mdl-35551153
ABSTRACT
COL1A1-PDGFB gene fusion uterine sarcoma is a recently described entity which shows some overlapping features with dermatofibrosarcoma protuberans. To date, only 4 cases have been reported in the literature. Due to its rarity, succinct clinicopathologic characteristics are yet to be established. We report a fifth case initially mistaken as a uterine fibroid which histologically proved to be a CD34 + high-grade spindle cell proliferation which on fluorescence in situ hybridization analysis displayed COL1A1-PDGFB gene rearrangement. With this case description we hope to raise awareness and aid in the characterization of this emerging entity.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin Neoplasms
/
Soft Tissue Neoplasms
/
Dermatofibrosarcoma
Limits:
Humans
Language:
En
Journal:
Int J Gynecol Pathol
Year:
2023
Document type:
Article
Affiliation country:
España