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Reversible lysine-targeted probes reveal residence time-based kinase selectivity.
Yang, Tangpo; Cuesta, Adolfo; Wan, Xiaobo; Craven, Gregory B; Hirakawa, Brad; Khamphavong, Penney; May, Jeffrey R; Kath, John C; Lapek, John D; Niessen, Sherry; Burlingame, Alma L; Carelli, Jordan D; Taunton, Jack.
Affiliation
  • Yang T; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.
  • Cuesta A; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.
  • Wan X; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.
  • Craven GB; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
  • Hirakawa B; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.
  • Khamphavong P; Pfizer Global Research and Development La Jolla, San Diego, CA, USA.
  • May JR; Pfizer Global Research and Development La Jolla, San Diego, CA, USA.
  • Kath JC; Pfizer Global Research and Development La Jolla, San Diego, CA, USA.
  • Lapek JD; Pfizer Global Research and Development La Jolla, San Diego, CA, USA.
  • Niessen S; Pfizer Global Research and Development La Jolla, San Diego, CA, USA.
  • Burlingame AL; Pfizer Global Research and Development La Jolla, San Diego, CA, USA.
  • Carelli JD; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
  • Taunton J; Pfizer Global Research and Development La Jolla, San Diego, CA, USA.
Nat Chem Biol ; 18(9): 934-941, 2022 09.
Article in En | MEDLINE | ID: mdl-35590003
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Lysine Limits: Animals Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Lysine Limits: Animals Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos