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A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice.
Sun, Bo; Ni, Mingke; Tian, Shanshan; Guo, Wenting; Cai, Shitian; Sondergaard, Mads T; Chen, Yongxiang; Mu, Yongxin; Estillore, John P; Wang, Ruiwu; Chen, Ju; Overgaard, Michael T; Fill, Michael; Ramos-Franco, Josefina; Nyegaard, Mette; Wayne Chen, Sui Rong.
Affiliation
  • Sun B; Department of Physiology and Pharmacology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
  • Ni M; Laboratory of Molecular Pharmacology, Medical School, Kunming University of Science and Technology, Kunming, China.
  • Tian S; Department of Physiology and Pharmacology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
  • Guo W; Department of Physiology and Pharmacology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
  • Cai S; Department of Physiology and Pharmacology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
  • Sondergaard MT; Department of Physiology and Pharmacology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
  • Chen Y; Department of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark.
  • Mu Y; Department of Physiology and Pharmacology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
  • Estillore JP; Department of Medicine, University of California at San Diego, La Jolla, California, USA.
  • Wang R; Department of Physiology and Pharmacology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
  • Chen J; Department of Physiology and Pharmacology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
  • Overgaard MT; Department of Medicine, University of California at San Diego, La Jolla, California, USA.
  • Fill M; Department of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark.
  • Ramos-Franco J; Department of Physiology and Biophysics, Rush University Medical Center, Chicago, Illinois, USA.
  • Nyegaard M; Department of Physiology and Biophysics, Rush University Medical Center, Chicago, Illinois, USA.
  • Wayne Chen SR; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
J Cell Physiol ; 237(8): 3305-3316, 2022 08.
Article in En | MEDLINE | ID: mdl-35621185

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inositol 1,4,5-Trisphosphate Receptors / Gain of Function Mutation / Infertility, Male Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: J Cell Physiol Year: 2022 Document type: Article Affiliation country: Canadá

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inositol 1,4,5-Trisphosphate Receptors / Gain of Function Mutation / Infertility, Male Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: J Cell Physiol Year: 2022 Document type: Article Affiliation country: Canadá