Automatic Programmable Bioreactor with pH Monitoring System for Tissue Engineering Application.
Bioengineering (Basel)
; 9(5)2022 Apr 25.
Article
in En
| MEDLINE
| ID: mdl-35621465
ABSTRACT
Tissue engineering technology has been advanced and applied to various applications in the past few years. The presence of a bioreactor is one key factor to the successful development of advanced tissue engineering products. In this work, we developed a programmable bioreactor with a controlling program that allowed each component to be automatically operated. Moreover, we developed a new pH sensor for non-contact and real-time pH monitoring. We demonstrated that the prototype bioreactor could facilitate automatic cell culture of L929 cells. It showed that the cell viability was greater than 80% and cell proliferation was enhanced compared to that of the control obtained by a conventional cell culture procedure. This result suggests the possibility of a system that could be potentially useful for medical and industrial applications, including cultured meat, drug testing, etc.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Bioengineering (Basel)
Year:
2022
Document type:
Article
Affiliation country:
Tailandia