Modern Biophysics Redefines Our Understanding of Fungal Cell Wall Structure, Complexity, and Dynamics.
mBio
; 13(3): e0114522, 2022 06 28.
Article
in En
| MEDLINE
| ID: mdl-35638742
ABSTRACT
Even though the cell wall has been recognized as a crucial protective organelle for fungi, essential for its virulence and a unique emblem of this kingdom, biosynthesis of this organelle remains poorly understood. Our knowledge was based mainly in the past on the chemical analysis of cell wall mutants and on the biochemical study of a few synthases and transglycosidases. Recent developments in biophysical equipment and methods, such as solid-state nuclear magnetic resonance or cryo-electron microscopy, have promoted a better appreciation of the spatiotemporal dynamics of cell wall biosynthesis. The new information will be presented here with the cell wall of the human opportunistic pathogen Aspergillus fumigatus.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Aspergillus fumigatus
/
Cell Wall
Limits:
Humans
Language:
En
Journal:
MBio
Year:
2022
Document type:
Article
Affiliation country:
Grecia