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A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex.
Antaki, Danny; Guevara, James; Maihofer, Adam X; Klein, Marieke; Gujral, Madhusudan; Grove, Jakob; Carey, Caitlin E; Hong, Oanh; Arranz, Maria J; Hervas, Amaia; Corsello, Christina; Vaux, Keith K; Muotri, Alysson R; Iakoucheva, Lilia M; Courchesne, Eric; Pierce, Karen; Gleeson, Joseph G; Robinson, Elise B; Nievergelt, Caroline M; Sebat, Jonathan.
Affiliation
  • Antaki D; Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, CA, USA.
  • Guevara J; Beyster Center for Psychiatric Genomics, University of California San Diego, La Jolla, CA, USA.
  • Maihofer AX; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
  • Klein M; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
  • Gujral M; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.
  • Grove J; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.
  • Carey CE; Beyster Center for Psychiatric Genomics, University of California San Diego, La Jolla, CA, USA.
  • Hong O; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
  • Arranz MJ; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
  • Hervas A; Beyster Center for Psychiatric Genomics, University of California San Diego, La Jolla, CA, USA.
  • Corsello C; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
  • Vaux KK; Beyster Center for Psychiatric Genomics, University of California San Diego, La Jolla, CA, USA.
  • Muotri AR; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
  • Iakoucheva LM; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Courchesne E; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.
  • Pierce K; Center for Genomics and Personalized Medicine and Center for Integrative Sequencing, iSEQ, Aarhus, Denmark.
  • Gleeson JG; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.
  • Robinson EB; Harvard T.H. Chan School of Public Health, Broad Institute of the Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.
  • Nievergelt CM; Beyster Center for Psychiatric Genomics, University of California San Diego, La Jolla, CA, USA.
  • Sebat J; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Nat Genet ; 54(9): 1284-1292, 2022 09.
Article in En | MEDLINE | ID: mdl-35654974
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autism Spectrum Disorder Type of study: Etiology_studies / Risk_factors_studies Limits: Child / Female / Humans / Male Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autism Spectrum Disorder Type of study: Etiology_studies / Risk_factors_studies Limits: Child / Female / Humans / Male Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos