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CRISPR activation screen identifies TGFß-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma.
Saratov, Vadim; Ngo, Quy A; Pedot, Gloria; Sidorov, Semjon; Wachtel, Marco; Niggli, Felix K; Schäfer, Beat W.
Affiliation
  • Saratov V; Department of Oncology and Children's Research Center, University Children's Hospital, Steinwiesstrasse 32, 8032, Zurich, Switzerland.
  • Ngo QA; Department of Oncology and Children's Research Center, University Children's Hospital, Steinwiesstrasse 32, 8032, Zurich, Switzerland.
  • Pedot G; Department of Oncology and Children's Research Center, University Children's Hospital, Steinwiesstrasse 32, 8032, Zurich, Switzerland.
  • Sidorov S; Experimental Infectious Diseases and Cancer Research, Children's Research Center, University Children's Hospital of Zurich, University of Zurich, Zurich, Switzerland.
  • Wachtel M; Department of Oncology and Children's Research Center, University Children's Hospital, Steinwiesstrasse 32, 8032, Zurich, Switzerland.
  • Niggli FK; Department of Oncology and Children's Research Center, University Children's Hospital, Steinwiesstrasse 32, 8032, Zurich, Switzerland.
  • Schäfer BW; Department of Oncology and Children's Research Center, University Children's Hospital, Steinwiesstrasse 32, 8032, Zurich, Switzerland. Beat.Schaefer@kispi.uzh.ch.
Sci Rep ; 12(1): 10671, 2022 06 23.
Article in En | MEDLINE | ID: mdl-35739280
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma, Ewing / RNA-Binding Proteins / Neuroectodermal Tumors, Primitive, Peripheral / DNA-Binding Proteins / Apoptosis Regulatory Proteins Type of study: Prognostic_studies / Risk_factors_studies Limits: Child / Humans Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Suiza Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma, Ewing / RNA-Binding Proteins / Neuroectodermal Tumors, Primitive, Peripheral / DNA-Binding Proteins / Apoptosis Regulatory Proteins Type of study: Prognostic_studies / Risk_factors_studies Limits: Child / Humans Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Suiza Country of publication: Reino Unido