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Mitochondrial SIRT3 Deficiency Results in Neuronal Network Hyperexcitability, Accelerates Age-Related Aß Pathology, and Renders Neurons Vulnerable to Aß Toxicity.
Perone, Isabella; Ghena, Nathaniel; Wang, Jing; Mackey, Chelsea; Wan, Ruiqian; Malla, Sulochan; Gorospe, Myriam; Cheng, Aiwu; Mattson, Mark P.
Affiliation
  • Perone I; Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, Baltimore, MD, 21224, USA.
  • Ghena N; Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD, 21224, USA.
  • Wang J; Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD, 21224, USA.
  • Mackey C; Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD, 21224, USA.
  • Wan R; Department of Integrative Medicine and Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China.
  • Malla S; Department of Integrative Medicine and Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China.
  • Gorospe M; Laboratory of Cardiovascular Science, National Institute on Aging Intramural Research Program, Baltimore, MD, 21224, USA.
  • Cheng A; Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD, 21224, USA.
  • Mattson MP; Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, Baltimore, MD, 21224, USA.
Neuromolecular Med ; 25(1): 27-39, 2023 03.
Article in En | MEDLINE | ID: mdl-35749057
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sirtuin 3 / Alzheimer Disease Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Neuromolecular Med Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2023 Document type: Article Affiliation country: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sirtuin 3 / Alzheimer Disease Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Neuromolecular Med Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2023 Document type: Article Affiliation country: Estados Unidos