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Cinnamoyloxy-mammeisin, a coumarin from propolis of stingless bees, attenuates Th17 cell differentiation and autoimmune inflammation via STAT3 inhibition.
Franchin, Marcelo; Luiz Rosalen, Pedro; da Silva Prado, Douglas; César Paraluppi, Murilo; Leal Silva, Rangel; Damasceno, Luis Eduardo Alves; Morelo, David Fernando Colon; Napimoga, Marcelo Henrique; Cunha, Fernando Q; Alves-Filho, José C; Cunha, Thiago M.
Affiliation
  • Franchin M; Department of Biosciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil; School of Dentistry, Federal University of Alfenas (Unifal-MG), Alfenas, Minas Gerais, Brazil. Electronic address: marcelo.franchin@unifal-mg.edu.br.
  • Luiz Rosalen P; Department of Biosciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil; Graduate Program in Biological Sciences, Federal University of Alfenas (Unifal-MG), Alfenas, MG, Brazil.
  • da Silva Prado D; Center for Research in Inflammatory Diseases, Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.
  • César Paraluppi M; Department of Biosciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil.
  • Leal Silva R; Center for Research in Inflammatory Diseases, Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.
  • Damasceno LEA; Center for Research in Inflammatory Diseases, Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.
  • Morelo DFC; Center for Research in Inflammatory Diseases, Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.
  • Napimoga MH; São Leopoldo Mandic Institute and Research Center, Laboratory of Neuroimmune Interface of Pain Research, Campinas, SP, Brazil.
  • Cunha FQ; Center for Research in Inflammatory Diseases, Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.
  • Alves-Filho JC; Center for Research in Inflammatory Diseases, Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.
  • Cunha TM; Center for Research in Inflammatory Diseases, Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. Electronic address: thicunha@usp.br.
Eur J Pharmacol ; 929: 175127, 2022 Aug 15.
Article in En | MEDLINE | ID: mdl-35787889
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propolis / Encephalomyelitis, Autoimmune, Experimental Limits: Animals / Humans Language: En Journal: Eur J Pharmacol Year: 2022 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propolis / Encephalomyelitis, Autoimmune, Experimental Limits: Animals / Humans Language: En Journal: Eur J Pharmacol Year: 2022 Document type: Article