The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment.

Huang, Zhou; Liu, Hejun; Nix, Jay; Xu, Rui; Knoverek, Catherine R; Bowman, Gregory R; Amarasinghe, Gaya K; Sibley, L David

Huang, Zhou; Liu, Hejun; Nix, Jay; Xu, Rui; Knoverek, Catherine R; Bowman, Gregory R; Amarasinghe, Gaya K; Sibley, L David.

Affiliation

Huang Z; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Liu H; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Nix J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA.
Xu R; Molecular Biology Consortium, Advanced Light Source, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Knoverek CR; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Bowman GR; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Amarasinghe GK; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Sibley LD; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Nat Commun ; 13(1): 4047, 2022 07 13.

Article in En | MEDLINE | ID: mdl-35831295

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Toxoplasma / Intrinsically Disordered Proteins Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: Estados Unidos

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