T helper profile in pregnant women recovered from COVID-19.
J Reprod Immunol
; 153: 103661, 2022 09.
Article
in En
| MEDLINE
| ID: mdl-35839525
ABSTRACT
T helper (Th) cell subsets play distinct and important roles during pregnancy. This work was focused on investigating the Th and cytokine profile in pregnant women recovered from COVID-19. To this aim, the frequency of Th1, Th2, Th17 subsets and the level of associated cytokines were analysed in pregnant women recovered from COVID-19 and in matched non-pregnant women. Principal component analysis highlighted a significant impact of pregnancy on Th profile with an increase of ex-Th17 subset and a parallel decrease of Th1 population. These modulations may participate in both preserving the pregnancy and reducing the risk of severe infection.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
T-Lymphocyte Subsets
/
COVID-19
Limits:
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
J Reprod Immunol
Year:
2022
Document type:
Article