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T helper profile in pregnant women recovered from COVID-19.
Tartaglia, Eleonora; Bordoni, Veronica; Oliva, Alessandra; Vergori, Alessandra; Girardi, Enrico; Antinori, Andrea; Agrati, Chiara; Liuzzi, Giuseppina.
Affiliation
  • Tartaglia E; INMI L. Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. Electronic address: eleonora.tartaglia@inmi.it.
  • Bordoni V; INMI L. Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. Electronic address: veronica.bordoni@inmi.it.
  • Oliva A; INMI L. Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. Electronic address: alessandra.oliva@inmi.it.
  • Vergori A; INMI L. Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. Electronic address: alessandra.vergori@inmi.it.
  • Girardi E; INMI L. Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. Electronic address: enrico.girardi@inmi.it.
  • Antinori A; INMI L. Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. Electronic address: andrea.antinori@inmi.it.
  • Agrati C; INMI L. Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. Electronic address: chiara.agrati@inmi.it.
  • Liuzzi G; INMI L. Spallanzani - IRCCS, Via Portuense 292, 00149 Rome, Italy. Electronic address: giuseppina.liuzzi@inmi.it.
J Reprod Immunol ; 153: 103661, 2022 09.
Article in En | MEDLINE | ID: mdl-35839525
ABSTRACT
T helper (Th) cell subsets play distinct and important roles during pregnancy. This work was focused on investigating the Th and cytokine profile in pregnant women recovered from COVID-19. To this aim, the frequency of Th1, Th2, Th17 subsets and the level of associated cytokines were analysed in pregnant women recovered from COVID-19 and in matched non-pregnant women. Principal component analysis highlighted a significant impact of pregnancy on Th profile with an increase of ex-Th17 subset and a parallel decrease of Th1 population. These modulations may participate in both preserving the pregnancy and reducing the risk of severe infection.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocyte Subsets / COVID-19 Limits: Female / Humans / Pregnancy Language: En Journal: J Reprod Immunol Year: 2022 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocyte Subsets / COVID-19 Limits: Female / Humans / Pregnancy Language: En Journal: J Reprod Immunol Year: 2022 Document type: Article