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SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation.
Xu, Zhang; Choi, Jung-Hyun; Dai, David L; Luo, Jun; Ladak, Reese Jalal; Li, Qian; Wang, Yimeng; Zhang, Christine; Wiebe, Shane; Liu, Alex C H; Ran, Xiaozhuo; Yang, Jiaqi; Naeli, Parisa; Garzia, Aitor; Zhou, Lele; Mahmood, Niaz; Deng, Qiyun; Elaish, Mohamed; Lin, Rongtuan; Mahal, Lara K; Hobman, Tom C; Pelletier, Jerry; Alain, Tommy; Vidal, Silvia M; Duchaine, Thomas; Mazhab-Jafari, Mohammad T; Mao, Xiaojuan; Jafarnejad, Seyed Mehdi; Sonenberg, Nahum.
Affiliation
  • Xu Z; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Choi JH; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Dai DL; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Luo J; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Ladak RJ; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON M5G 2C1, Canada.
  • Li Q; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Wang Y; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Zhang C; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Wiebe S; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Liu ACH; Meakins-Christie Laboratories and Respiratory Division, McGill University, Montreal, QC, H4A 3J1, Canada.
  • Ran X; Lady Davis Institute, Department of Medicine, McGill University, Montreal, QC, H3T 1E2, Canada.
  • Yang J; Department of Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, MB, R3T 2N2, Canada.
  • Naeli P; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Garzia A; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Zhou L; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON M5G 2C1, Canada.
  • Mahmood N; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON M5G 2C1, Canada.
  • Deng Q; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON M5G 2C1, Canada.
  • Elaish M; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, Northern Ireland, BT9 7AE, United Kingdom.
  • Lin R; Laboratory for RNA Molecular Biology, The Rockefeller University, New York, NY 10065.
  • Mahal LK; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Hobman TC; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Pelletier J; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Alain T; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Vidal SM; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Duchaine T; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Mazhab-Jafari MT; Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada.
  • Mao X; Department of Cell Biology, University of Alberta, Edmonton, AB T6G 2H7, Canada.
  • Jafarnejad SM; Poultry Diseases Department, Faculty of Veterinary Medicine, Cairo University, Giza, 12613 Egypt.
  • Sonenberg N; Lady Davis Institute, Department of Medicine, McGill University, Montreal, QC, H3T 1E2, Canada.
Proc Natl Acad Sci U S A ; 119(32): e2204539119, 2022 08 09.
Article in En | MEDLINE | ID: mdl-35878012
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carrier Proteins / Interferon Type I / Viral Nonstructural Proteins / COVID-19 Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Affiliation country: Canadá Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carrier Proteins / Interferon Type I / Viral Nonstructural Proteins / COVID-19 Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Affiliation country: Canadá Country of publication: Estados Unidos