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Comparative Analysis of the Chemotherapy-Related Cognitive Impairments in Patients with Breast Cancer: A Community-Based Research.
Owrangi, Maryam; Gholamzadeh, Mohammad Javad; Vasaghi Gharamaleki, Maryam; Mousavi, Seyedeh Zahra; Kamali, Ali-Mohammad; Dehghani, Mehdi; Chakrabarti, Prasun; Nami, Mohammad.
Affiliation
  • Owrangi M; Students' Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Gholamzadeh MJ; Students' Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Vasaghi Gharamaleki M; Students' Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Mousavi SZ; Students' Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Kamali AM; Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Dehghani M; Iranian Neuroscience Society-Fars Chapter, DANA Brain Health Institute, Shiraz, Iran.
  • Chakrabarti P; Hematology Research Center, Department of Hematology and Medical Oncology, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Nami M; ITM SLS Baroda University Vadodara, Paldi, India.
Cancer Invest ; 40(9): 811-821, 2022 Oct.
Article in En | MEDLINE | ID: mdl-35880822
ABSTRACT
This study aimed to evaluate the effects of two common chemotherapy regimens on breast cancer (BC) survivors' cognition. The participants comprised 35 patients with BC who underwent two chemotherapy regimens, AC-T and TAC, and 24 matched healthy volunteers. The participants were assessed regarding cognitive function through Addenbrooke's Cognitive Examination and Cambridge Brain Science tests. The results represent the AC-T regimen to be more toxic than the TAC in domains of language, concentration, and visuospatial working memory (P-value = 0.036, 0.008, and 0.031, respectively) and should be prescribed with caution in patients with BC suffering from baseline cognitive impairments.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Cognitive Dysfunction / Chemotherapy-Related Cognitive Impairment Type of study: Diagnostic_studies Limits: Female / Humans Language: En Journal: Cancer Invest Year: 2022 Document type: Article Affiliation country: Irán
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Cognitive Dysfunction / Chemotherapy-Related Cognitive Impairment Type of study: Diagnostic_studies Limits: Female / Humans Language: En Journal: Cancer Invest Year: 2022 Document type: Article Affiliation country: Irán