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Imeglimin exerts favorable effects on pancreatic ß-cells by improving morphology in mitochondria and increasing the number of insulin granules.
Sanada, Junpei; Obata, Atsushi; Fushimi, Yoshiro; Kimura, Tomohiko; Shimoda, Masashi; Ikeda, Tomoko; Nogami, Yuka; Obata, Yoshiyuki; Yamasaki, Yuki; Nakanishi, Shuhei; Mune, Tomoatsu; Kaku, Kohei; Kaneto, Hideaki.
Affiliation
  • Sanada J; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Obata A; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Fushimi Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Kimura T; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Shimoda M; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Ikeda T; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Nogami Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Obata Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Yamasaki Y; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Nakanishi S; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Mune T; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Kaku K; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
  • Kaneto H; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan. kaneto@med.kawasaki-m.ac.jp.
Sci Rep ; 12(1): 13220, 2022 08 02.
Article in En | MEDLINE | ID: mdl-35918386
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Experimental / Diabetes Mellitus, Type 2 / Insulin-Secreting Cells Limits: Animals Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Japón Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Experimental / Diabetes Mellitus, Type 2 / Insulin-Secreting Cells Limits: Animals Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Japón Country of publication: Reino Unido