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Examining Treatment Outcomes Across Contexts: How Do Child Baseline Characteristics Impact Measurement of Treatment Response?
Grzadzinski, Rebecca; Jatkar, Alapika; Donovan, Kevin; Truong, Kinh; Holbrook, Alison; Lord, Catherine; Kim, So Hyun.
Affiliation
  • Grzadzinski R; Carolina Institute for Developmental Disabilities, University of North Carolina, Chapel Hill, NC, USA.
  • Jatkar A; Program for Early Autism Research Leadership and Service (PEARLS), University of North Carolina, Chapel Hill, NC, USA.
  • Donovan K; Carolina Institute for Developmental Disabilities, University of North Carolina, Chapel Hill, NC, USA.
  • Truong K; Penn Statistics in Imaging and Visualization Endeavor (PennSIVE), Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.
  • Holbrook A; Gillings School of Global Public Health, Department of Biostatistics, Chapel Hill, USA.
  • Lord C; The Simons Foundation, New York, NY, USA.
  • Kim SH; Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, USA.
J Autism Dev Disord ; 53(11): 4121-4131, 2023 Nov.
Article in En | MEDLINE | ID: mdl-35969334
ABSTRACT
The evaluation of the overlap between the ADOS BOSCC and Standard BOSCC as well as the exploration of child characteristics that may predict change are important steps in consolidating data-driven definitions of "improvement". Participants were seen between 2 and 5 times with Standard BOSCC and ADOS BOSCC observations over the course of early intervention trials (Grzadzinski et al. in J Autism Dev Disord 462464, 2016; Kim et al. in Autism 235, 2019). Results showed consistency between the Standard BOSCC and ADOS BOSCC, highlighting the utility of both as metrics of change and treatment outcome across contexts. Baseline characteristics may play a role in the tailoring of early intervention to maximize treatment outcome and may offer guidance when determining which outcome measures to use.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autism Spectrum Disorder Type of study: Guideline / Prognostic_studies Limits: Child / Humans Language: En Journal: J Autism Dev Disord Year: 2023 Document type: Article Affiliation country: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autism Spectrum Disorder Type of study: Guideline / Prognostic_studies Limits: Child / Humans Language: En Journal: J Autism Dev Disord Year: 2023 Document type: Article Affiliation country: Estados Unidos