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IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells.
Remsing Rix, Lily L; Sumi, Natalia J; Hu, Qianqian; Desai, Bina; Bryant, Annamarie T; Li, Xueli; Welsh, Eric A; Fang, Bin; Kinose, Fumi; Kuenzi, Brent M; Chen, Y Ann; Antonia, Scott J; Lovly, Christine M; Koomen, John M; Haura, Eric B; Marusyk, Andriy; Rix, Uwe.
Affiliation
  • Remsing Rix LL; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Sumi NJ; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Hu Q; Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL 33620, USA.
  • Desai B; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Bryant AT; Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL 33620, USA.
  • Li X; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Welsh EA; Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL 33620, USA.
  • Fang B; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Kinose F; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Kuenzi BM; Biostatistics and Bioinformatics Shared Resource, Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Chen YA; Proteomics and Metabolomics Core, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.
  • Antonia SJ; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.
  • Lovly CM; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Koomen JM; Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL 33620, USA.
  • Haura EB; Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Marusyk A; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33620, USA.
  • Rix U; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.
Sci Signal ; 15(747): eabj5879, 2022 08 16.
Article in En | MEDLINE | ID: mdl-35973030
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cancer-Associated Fibroblasts / Lung Neoplasms Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cancer-Associated Fibroblasts / Lung Neoplasms Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos