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The lonidamine derivative H2-gamendazole reduces cyst formation in polycystic kidney disease.
Sundar, Shirin V; Zhou, Julie Xia; Magenheimer, Brenda S; Reif, Gail A; Wallace, Darren P; Georg, Gunda I; Jakkaraj, Sudhakar R; Tash, Joseph S; Yu, Alan S L; Li, Xiaogang; Calvet, James P.
Affiliation
  • Sundar SV; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas.
  • Zhou JX; Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas.
  • Magenheimer BS; Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas.
  • Reif GA; Division of Nephrology and Hypertension, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.
  • Wallace DP; Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.
  • Georg GI; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota.
  • Jakkaraj SR; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas.
  • Tash JS; Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas.
  • Yu ASL; Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas.
  • Li X; Division of Nephrology and Hypertension, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas.
  • Calvet JP; Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas.
Am J Physiol Renal Physiol ; 323(4): F492-F506, 2022 10 01.
Article in En | MEDLINE | ID: mdl-35979967
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycystic Kidney, Autosomal Dominant / Cysts / Polycystic Kidney Diseases Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Am J Physiol Renal Physiol Journal subject: FISIOLOGIA / NEFROLOGIA Year: 2022 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycystic Kidney, Autosomal Dominant / Cysts / Polycystic Kidney Diseases Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Am J Physiol Renal Physiol Journal subject: FISIOLOGIA / NEFROLOGIA Year: 2022 Document type: Article