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Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies.
Scheepers, Cathrine; Kgagudi, Prudence; Mzindle, Nonkululeko; Gray, Elin S; Moyo-Gwete, Thandeka; Lambson, Bronwen E; Oosthuysen, Brent; Mabvakure, Batsirai; Garrett, Nigel J; Abdool Karim, Salim S; Morris, Lynn; Moore, Penny L.
Affiliation
  • Scheepers C; Centre for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
  • Kgagudi P; SA MRC Antibody Immunity Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa.
  • Mzindle N; Centre for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
  • Gray ES; SA MRC Antibody Immunity Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa.
  • Moyo-Gwete T; Centre for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
  • Lambson BE; SA MRC Antibody Immunity Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa.
  • Oosthuysen B; Centre for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
  • Mabvakure B; Centre for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
  • Garrett NJ; SA MRC Antibody Immunity Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa.
  • Abdool Karim SS; Centre for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
  • Morris L; SA MRC Antibody Immunity Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa.
  • Moore PL; Centre for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
PLoS Pathog ; 18(9): e1010450, 2022 09.
Article in En | MEDLINE | ID: mdl-36054228
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / AIDS Vaccines Limits: Humans Language: En Journal: PLoS Pathog Year: 2022 Document type: Article Affiliation country: Sudáfrica Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / AIDS Vaccines Limits: Humans Language: En Journal: PLoS Pathog Year: 2022 Document type: Article Affiliation country: Sudáfrica Country of publication: Estados Unidos