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Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian cancer.
Achreja, Abhinav; Yu, Tao; Mittal, Anjali; Choppara, Srinadh; Animasahun, Olamide; Nenwani, Minal; Wuchu, Fulei; Meurs, Noah; Mohan, Aradhana; Jeon, Jin Heon; Sarangi, Itisam; Jayaraman, Anusha; Owen, Sarah; Kulkarni, Reva; Cusato, Michele; Weinberg, Frank; Kweon, Hye Kyong; Subramanian, Chitra; Wicha, Max S; Merajver, Sofia D; Nagrath, Sunitha; Cho, Kathleen R; DiFeo, Analisa; Lu, Xiongbin; Nagrath, Deepak.
Affiliation
  • Achreja A; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Yu T; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Mittal A; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Choppara S; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
  • Animasahun O; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Nenwani M; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Wuchu F; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Meurs N; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Mohan A; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Jeon JH; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Sarangi I; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Jayaraman A; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Owen S; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Kulkarni R; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Cusato M; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Weinberg F; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Kweon HK; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Subramanian C; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Wicha MS; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Merajver SD; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Nagrath S; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Cho KR; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • DiFeo A; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
  • Lu X; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.
  • Nagrath D; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Nat Metab ; 4(9): 1119-1137, 2022 09.
Article in En | MEDLINE | ID: mdl-36131208
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Multifunctional Enzymes / Aminohydrolases / Methylenetetrahydrofolate Dehydrogenase (NADP) Type of study: Diagnostic_studies Limits: Female / Humans Language: En Journal: Nat Metab Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Alemania
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Multifunctional Enzymes / Aminohydrolases / Methylenetetrahydrofolate Dehydrogenase (NADP) Type of study: Diagnostic_studies Limits: Female / Humans Language: En Journal: Nat Metab Year: 2022 Document type: Article Affiliation country: Estados Unidos Country of publication: Alemania