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A Photoactivated Sorafenib-Ruthenium(II) Prodrug for Resistant Hepatocellular Carcinoma Therapy through Ferroptosis and Purine Metabolism Disruption.
Lai, Yidan; Lu, Nong; Luo, Shuangling; Wang, Haobing; Zhang, Pingyu.
Affiliation
  • Lai Y; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, China.
  • Lu N; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, China.
  • Luo S; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, China.
  • Wang H; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, China.
  • Zhang P; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, China.
J Med Chem ; 65(19): 13041-13051, 2022 10 13.
Article in En | MEDLINE | ID: mdl-36134739
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ruthenium / Prodrugs / Carcinoma, Hepatocellular / Ferroptosis / Liver Neoplasms / Antineoplastic Agents Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2022 Document type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ruthenium / Prodrugs / Carcinoma, Hepatocellular / Ferroptosis / Liver Neoplasms / Antineoplastic Agents Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2022 Document type: Article Affiliation country: China