Deleting Gata4 in hepatocytes promoted the progression of NAFLD via increasing steatosis and apoptosis, and desensitizing insulin signaling.

He, Leya; Wang, Xian; Ding, Zehuan; Liu, Lin; Cheng, Henghui; Bily, Donalyn; Wu, Chaodong; Zhang, Ke; Xie, Linglin

He, Leya; Wang, Xian; Ding, Zehuan; Liu, Lin; Cheng, Henghui; Bily, Donalyn; Wu, Chaodong; Zhang, Ke; Xie, Linglin.

Affiliation

He L; Department of Nutrition, Texas A&M University, College Station, TX, 77843, USA.
Wang X; Department of Nutrition, Texas A&M University, College Station, TX, 77843, USA.
Ding Z; Department of Nutrition, Texas A&M University, College Station, TX, 77843, USA.
Liu L; Department of Nutrition, Texas A&M University, College Station, TX, 77843, USA.
Cheng H; Department of Nutrition, Texas A&M University, College Station, TX, 77843, USA.
Bily D; Department of Nutrition, Texas A&M University, College Station, TX, 77843, USA.
Wu C; Department of Nutrition, Texas A&M University, College Station, TX, 77843, USA.
Zhang K; Department of Nutrition, Texas A&M University, College Station, TX, 77843, USA; Institute of Biosciences & Technology, Texas A&M University, Houston, TX, 77030, USA.
Xie L; Department of Nutrition, Texas A&M University, College Station, TX, 77843, USA. Electronic address: linglin.xie@tamu.edu.

J Nutr Biochem ; 111: 109157, 2023 01.

Article in En | MEDLINE | ID: mdl-36150682

Subject(s)
Key words

Apoptosis; Gata4; Hepatocytes; Insulin signaling; NAFLD

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Non-alcoholic Fatty Liver Disease Limits: Animals Language: En Journal: J Nutr Biochem Journal subject: BIOQUIMICA / CIENCIAS DA NUTRICAO Year: 2023 Document type: Article Affiliation country: Estados Unidos

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