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Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects in brain regions associated with addiction.
Kember, Rachel L; Vickers-Smith, Rachel; Xu, Heng; Toikumo, Sylvanus; Niarchou, Maria; Zhou, Hang; Hartwell, Emily E; Crist, Richard C; Rentsch, Christopher T; Davis, Lea K; Justice, Amy C; Sanchez-Roige, Sandra; Kampman, Kyle M; Gelernter, Joel; Kranzler, Henry R.
Affiliation
  • Kember RL; Mental Illness Research, Education and Clinical Center, Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.
  • Vickers-Smith R; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Xu H; Mental Illness Research, Education and Clinical Center, Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.
  • Toikumo S; Department of Epidemiology, University of Kentucky College of Public Health, Lexington, KY, USA.
  • Niarchou M; Center on Drug and Alcohol Research, Department of Behavioral Science, University of Kentucky College of Medicine, Lexington, KY, USA.
  • Zhou H; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Hartwell EE; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Crist RC; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Rentsch CT; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.
  • Davis LK; Mental Illness Research, Education and Clinical Center, Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.
  • Justice AC; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Sanchez-Roige S; Mental Illness Research, Education and Clinical Center, Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.
  • Kampman KM; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Gelernter J; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.
  • Kranzler HR; Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Nat Neurosci ; 25(10): 1279-1287, 2022 10.
Article in En | MEDLINE | ID: mdl-36171425
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Behavior, Addictive / Opioid-Related Disorders Type of study: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2022 Document type: Article Affiliation country: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Behavior, Addictive / Opioid-Related Disorders Type of study: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2022 Document type: Article Affiliation country: Estados Unidos